A lingering cough, ongoing tiredness or changes in digestion are often caused by minor illnesses and usually settle on their own.
However, if a symptom is persistent, unusual or simply doesn’t feel right for you, it’s worth getting it checked. In many cases there’s a straightforward explanation, but early assessment can provide reassurance or identify when further investigation is needed.
Here are 10 symptoms you shouldn’t ignore.
1. Fatigue that doesn’t improve
Everyone feels tired occasionally, but ongoing fatigue that doesn’t improve with rest may have an underlying cause, such as iron deficiency, thyroid problems, diabetes, poor sleep or menopause. If tiredness is affecting your daily life, it’s worth speaking to a GP.
2. Unexplained weight loss
Losing weight without trying should always be assessed, particularly if the change is significant or persistent. There are many possible causes, ranging from digestive conditions to hormonal disorders.
3. A persistent cough
Most coughs improve within a few weeks. If yours lasts longer than three weeks, is getting worse or is accompanied by symptoms such as coughing up blood, chest pain or breathlessness, seek medical advice.
4. Changes to a mole or skin lesion
Most moles are harmless, but any mole that changes in size, shape or colour, or starts itching, bleeding or crusting, should be checked by a healthcare professional.
5. Blood where it shouldn’t be
Whether it’s blood in your urine, stool, when coughing or unexpected vaginal bleeding, it’s important to have it assessed. While there are many non-serious causes, some require prompt investigation.
6. Persistent bloating
Occasional bloating is common, but bloating that lasts for several weeks or keeps returning—particularly alongside pelvic pain, changes in bowel habits or feeling full quickly—shouldn’t be ignored.
7. Changes in your bowel habit
If you notice persistent diarrhoea, constipation or another change in your normal bowel habit that lasts for several weeks, it’s worth booking an appointment, especially if it’s accompanied by abdominal pain, blood in your stool or unexplained weight loss.
8. Pelvic pain
Persistent or recurring pelvic pain isn’t something you should simply put up with. There are many possible causes, and a GP can help determine whether further investigation is needed.
9. Frequent urinary symptoms
Pain when passing urine, needing to go more often than usual or recurrent urinary tract infections may indicate an underlying problem, particularly if symptoms keep returning.
10. A lump or swelling that doesn’t go away
Many lumps are harmless, but any new lump that persists, grows or feels unusual should always be examined by a healthcare professional.
When should you see a GP?
Consider booking an appointment if a symptom:
Trust your instincts. If something doesn’t feel right, it’s always better to seek advice than continue worrying.
How Bond Medical can help
At Bond Medical, our experienced GPs take the time to understand your symptoms and medical history before recommending any investigations or treatment. Whether you have a new concern or simply want reassurance, we’re here to provide personalised, evidence-based care in a calm and unhurried environment.
Book a private GP appointment
If you’ve noticed a symptom that doesn’t feel quite right, our experienced GPs are here to help. Early assessment can often provide reassurance, and where needed, ensure you receive the right investigations and treatment.
References
Cancer Research UK (2025) Symptoms of cancer. Available at: https://www.cancerresearchuk.org/about-cancer/cancer-symptoms (Accessed: 6 August 2026).
National Institute for Health and Care Excellence (NICE) (2023) Suspected cancer: recognition and referral (NG12). Available at: https://www.nice.org.uk/guidance/ng12 (Accessed: 6 August 2026).
NHS (2025) Persistent cough. Available at: https://www.nhs.uk/conditions/cough/ (Accessed: 6 August 2026).
NHS (2025) Symptoms and when to get medical help. Available at: https://www.nhs.uk (Accessed: 6 August 2026).
NHS (2025) Tiredness and fatigue. Available at: https://www.nhs.uk/symptoms/tiredness-and-fatigue/ (Accessed: 6 August 2026).
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